0038US_niteworks_orangemango-300x300Many years ago, I believed Nitric Oxide (NO) existed in the arteries, yet I had to prove what I felt in my gut to be true. Like any scientist hoping to prove a hypothesis, I designed a number of experiments. Many of them failed; a few of them uncovered incredible findings.

One particular day, I was working on a cow aorta, mixing arterial extracts with various components and, at the same time, measuring NO (using a sensitive assay that had taken us over six months to develop). As the mixing started, my team and I detected NO. Then, we added vitamin C. Just two or three seconds after the addition of vitamin C—wow!—there it was, lots of NO being produced. Not only that, but the addition of vitamin C helped NO hang around a lot longer, from 0.1 seconds up to a full 30 seconds, allowing more time to capture the powerful substance. After all the hard work and years of believing in my hypothesis, that was the most exciting and rewarding moment in my basic research career.

Of course, years later, I sought to use what I found in the laboratory to help support human health. That’s why Niteworks® contains the antioxidants vitamin C and vitamin E, along with other key ingredients.

Ascorbic acid, or vitamin C, is a water-soluble antioxidant that promotes endothelial function and provides general antioxidant support against free radicals. By supporting the health of the endothelium, it also helps support the production of NO, a critical molecule for cardiovascular health. As I found in my experiments with the cow aorta, vitamin C extends the life of NO, extending its effect in the body.

I later found that adding alpha-tocopherol, or vitamin E, is a good addition to an endothelium-supportive combination. Vitamin E is a fat-soluble antioxidant that works in conjunction with vitamin C to support the health of the endothelium and entire body. Specifically, it helps stabilize and protect the membranes of endothelial cells from free radical damage. Again, when the endothelium is healthy, NO production is at its peak, which supports the wellness of the entire cardiovascular system.

Scientists continue to find uses for a combination of vitamins C and E to support heart health. Additional research is showing the potential for combining the two to help support endothelial health and NO production.

It’s incredible for me to look back on that moment—standing over the cow aorta, stunned by the incredible achievement in my research, grateful that I kept going all those years—and realize that my research is benefitting the many people who take Niteworks® dietary supplement.  Do you take Niteworks®? Let me know in the comments below; it’s an honor to see how my research has impacted your lives.